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N-TERMINAL KINASE, C-JUN
Descriptors Found:
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DeCS
Descriptor
English
:
JNK Mitogen-Activated Protein Kinases
Descriptor
Spanish
:
Proteínas Quinasas JNK Activadas por Mitógenos
Descriptor
Portuguese
:
Proteínas Quinases JNK Ativadas por Mitógeno
Synonyms
English
:
Amino-Terminal Kinase, c-jun
JNK Mitogen Activated Protein Kinases
N-Terminal Kinase, c-jun
c jun Amino Terminal Kinase
c jun N Terminal Kinase
c-jun Amino-Terminal Kinase
c-jun N-Terminal Kinase
jun NH2 Terminal Kinase
jun NH2 Terminal Kinases
jun-NH2-Terminal Kinase
jun-NH2-Terminal Kinases
Tree Number:
D08.811.913.696.620.682.700.567.374
D12.644.360.450.340
D12.776.476.450.340
Definition
English
:
A subgroup of
mitogen-activated protein kinases
that activate
TRANSCRIPTION FACTOR AP-1
via the
phosphorylation
of C-JUN
PROTEINS
. They are components of intracellular signaling pathways that regulate
CELL PROLIFERATION
;
APOPTOSIS
; and
CELL DIFFERENTIATION.
Indexing Annotation
English
:
note specifics
History Note
English
:
2005
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38731
Unique Identifier:
D048031
Occurrence in VHL
:
Similar:
DeCS